Talia Hale was the alpha of the Hale family and a guardian of Beacon Hills. She was able to shape-shift into a full wolf and was highly respected.
She knew Deucalion when he wanted to make peace with the Argents, although she advised against him trying.
Talia died in the Hale House fire.
All that could be found of her after the fire were five of her claws, which were kept in a special urn. Because claws are how werewolves share memories, Derek and Peter are able to use her claws with the mind meld ritual in order for Derek to speak to her ghost.